2013 NCAA Tournament: Four Upset Possibilities in the Round of 64

East Region 10-seed Colorado Buffaloes

March Madness started with a bang as Robert Morris took down the defending NCAA Tournament champion Kentucky Wildcats last night in the NIT.

Over on the senior circuit, North Carolina A&T edged Liberty to earn the right to play Louisville in the round of 64 while Matthew Dellavedova and Saint Mary's knocked off Middle Tennessee State and will face Memphis tomorrow.

Upsets generally rule the first second round of the tournament and this year should be no different. If the regular season was any indication of how March will play out, it's going to be one hell of a ride. Here's four matchups--one from each region--that have "upset possibility" written all over them. Keep in mind I'm just your average run-of-the-mill college basketball fan.

#10 Colorado over #7 Illinois (East)
Colorado is dangerous thanks to junior double-double machine Andre Roberson. Illinois might play in arguably the toughest league in the country but they are also one of the most inconsistent. They're heavily reliant on the three-pointer, something the Buffs defend extremely well. Roberson is a beast on the boards and seeing Illinois' struggles rebounding, this advantage should help propel the Buffaloes to the next round and a possible date with Miami (FL).

#15 Iona over #2 Ohio State (West)
Iona features one of the top scorers in the country in Lamont Jones and a secret weapon in David Laury (13.1 ppg, 10.4 rpg). Ohio State did win the Big Ten Tournament title but just ask Duke and Missouri how dangerous the #15 seed can be. Iona is a team that has been here before (second straight appearance) and knows how to win despite blowing a huge lead against BYU in a First Four game a season ago. The Buckeyes can play a clamp-down defense at times but they rarely face an offense as dynamic as the Gaels'.

#12 Oregon over #5 Oklahoma State (Midwest)
The Ducks won the Pac-12 and still got a 12-seed so to say they're playing with a chip on their shoulder is probably an understatement. A top-10 team for part of the regular season, they boast some athletic wings and senior Arsalan Kazemi (9.3 ppg, 9.5 rpg). Oklahoma State has standouts Marcus Smart and Markel Brown but their rebounding deficiency might cost them against a hungry Oregon squad.

#12 Akron over #5 VCU (South)
The Zips had a 19-game winning streak earlier in the season but are just 2-3 over the last five, but take nothing away from Akron, they're a quality basketball team. Shaka Smart has VCU primed up for another run into March but it's not the draw you'd expect for a team that's proven itself year after year. Both teams can score in bunches with the edge going to VCU but once again, rebounding questions surround this game. VCU is average on the boards but Akron really gets after it, thanks in large part to Demetrius Treadwell (7.9 rpg) and Zeke Marshall (7.1 rpg). The Rams are 10-3 over their last 13 games including a thrashing of #20 Butler on March 2. Akron is a confident team despite their recent ups and downs and should not be taken lightly.